Intro-Histology

Study Guide

1. Define and describe the scope of anatomy and physiology of the human body.  Explain the meaning and importance of complementarity to learning anatomy and physiology.

2. Identify and define the organizational hierarchy of living organisms and the significance of this hierarchy. Terms: cells, tissues, organs, systems. Identify the principle systems of the human body along with their functions and organs.

3. Identify the fundamental processes performed by all living organisms.  Give examples for the human body.

4. Define and describe homeostasis as it occurs in the human body and the importance of feedback in the control of homeostasis. Differentiate between positive and negative feedback and describe the situations in which each would be used. Be able to diagram or recognize the components of a feedback loop.

5. Identify and compare the characteristics and functions of the four major tissue types: epithelial, connective, muscular, nervous.

6. Describe the characteristics, functions, locations in the body and nomenclature for epithelial tissue. Include the characteristics of cellularity (arrangement of cells), cellular contacts or junctions (junctional complex), polarity (orientation), vascularity (presence of blood vessels), and support. Terms: tight junctions, desmosomes, hemidesmosomes, gap junctions, apical surface, basal surface, basal lamina, reticular lamina, basement membrane, microvilli, connexons, intermediate fibers, keratin; nomenclature: simple, stratified, pseudostratified, ciliated, squamous, cuboidal, columnar, transitional.

7. Identify the locations and functions of the following specific types of epithelial tissue: simple squamous epithelium, stratified squamous epithelium, simple columnar epithelium, simple cuboidal epithelium, pseudostratified ciliated columnar epithelium, ciliated columnar epithelium, transitional epithelium. Terms: endothelium, mesothelium, goblet cell, mucus, keratinized, non-keratinized, epidermis.

8. Identify major characteristics, and their related functions, of connective tissue. Include: cellularity, vascularity, Terms: mesenchyme, matrix, ground substance, loose connective tissue, dense connective tissue, inorganic salts, semisolid gel, collagen fibers, elastic fibers (elastin), reticular fibers cell adhesion proteins, proteoglycans, glycosaminoglycans (GAGs), (chondroitin sulfate, heparan sulfate, hyaluronic acid).

9. Identify the cells, and their functions, found in connective tissue. Include: fibrocyte (-blast,-clast), osteocyte (-blast, -clast), chondrocyte (-blast, -clast), plasma cells, mast cells, macrophages.

10. Describe the structural characteristics, locations and functions of the following specific connective tissues: areolar, adipose, dense regular (fibrous), dense irregular, elastic, reticular, hyaline cartilage, elastic cartilage, fibrocartilage, osseous (bone) tissue. Terms: interstitial fluid, stroma, ligaments, tendons, lacunae, perichondrium.

11. Identify the epithelial membranes found in the body and describe the tissue components, locations and functions of each. Terms: serous, mucous, cutaneous, mesentery, pericardial, pleural, peritoneal.

12. Compare the tissues studied as to their vascularity and ability to repair damage. Terms: regeneration, stroma, fibrosis, granulation tissue, parenchyma, scar tissue, adhesions.

13. Identify the basic causes and characteristics of cancer. Terms: oncogene, proto-oncogene, tumor suppressor gene, mutation, metastasis, apoptosis.