basophils- rare except during infections where these cells mediate inflammation by secreting histamine and heparan sulfate (related to the anticoagulant heparin). Histamine makes blood vessels permeable and heparin inhibits blood clotting. Basophils are functionally related to mast cells.
	eosinophils - also rare except during allergic reactions, these cells counteract the action of the basophils by secreting an anti-histamine (histaminase) and other enzymes which combat inflammation in allergies, they help to remove antigen-antibody complexes, and also are high during defense against multicellular parasites.