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Fatty
cholesterol-containing plaque along the lining of
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arteries.
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Due
to damage to vessel walls, e.g. from hypertension.
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Macrophages
responding to this damage cause
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inflammation
and begin to accumulate abundant
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cholesterol
and LDL (Low Density Lipoproteins).
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Smooth
muscle cells grow into the lining and form the
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framework
of the plaque incorporating the fat-laden
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macrophages.
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